GLIMPRINT Global Alliance for Immune Prediction and Intervention

Seminars

Explore our latest seminars on immune prediction and modeling.

Sepsis remains one of the leading causes of death in intensive care units worldwide — and modern medicine still lacks effective molecular therapies to treat the underlying immune dysfunction. In this talk, Dr. Gary An presents a National Academies of Sciences, Engineering, and Medicine (NASEM)-compliant digital twin designed specifically to control and reverse critical illness through adaptive, personalized immune intervention.

Rather than relying on population averages, predictive AI, or static models, this approach treats sepsis as a dynamic control problem, integrating:
February 27, 2026, 03:00 PM EST (1 hour)

Dr. Cliburn Chan introduces the Multiscale Immune Systems Modeling Center (MISM), a new NIAID-funded U54 Center of Excellence focused on bridging biological scales to enable future immune digital twins. MISM integrates AI, scientific machine learning, Bayesian modeling, and multiscale simulation to connect molecular, cellular, tissue, individual, and population-level immune processes. The center combines generative AI, agent-based modeling, organ-on-chip systems, and epidemiological network models to study immune diversity, disease transmission, and immune system complexity. Beyond research, MISM emphasizes model standardization, data sharing, interoperability, and community coordination to build reusable, scalable, and clinically relevant digital twin infrastructures for immunology and infectious disease modeling.

If you found this video useful, please check out our other videos on computational modeling, infection and immunology:
February 10, 2026, 03:00 PM EST (1 hour)