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Dr. Cliburn Chan introduces the Multiscale Immune Systems Modeling Center (MISM), a new NIAID-funded U54 Center of Excellence focused on bridging biological scales to enable future immune digital twins. MISM integrates AI, scientific machine learning, Bayesian modeling, and multiscale simulation to connect molecular, cellular, tissue, individual, and population-level immune processes. The center combines generative AI, agent-based modeling, organ-on-chip systems, and epidemiological network models to study immune diversity, disease transmission, and immune system complexity. Beyond research, MISM emphasizes model standardization, data sharing, interoperability, and community coordination to build reusable, scalable, and clinically relevant digital twin infrastructures for immunology and infectious disease modeling.
If you found this video useful, please check out our other videos on computational modeling, infection and immunology:
Please consider joining our IMAG/MSM WG on Multiscale Modeling and Viral Pandemics: https://www.imagwiki.nibib.nih.gov/content/msm-viral-pandemics-meetings
Abstract
Please also consider joining the Global Alliance for Immune Prediction and Intervention: http://glimprint.org/
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