Coupled Simulations in Theory and Practice

Simulations are used widely in engineering and in the related engineering sciences, but computational approaches are increasingly prevalent in other fields as well. Global challenges like climate change and the energy transition, land use change and biodiversity loss, and keeping an aging and strongly interconnected population healthy lead to scientists being asked not just to understand the complex systems underlying these changes, but to give concrete advice on how to steer these systems towards a better future. A key technical challenge in building the complex simulation models required to do this, is how to combine simulations of different but interacting processes. Modelling the interactions is system-specific and part of creating the model, but typically doesn't solve the question of what information to communicate when from where to where when it comes time to implement the simulation. This presentation introduces the Multiscale Modelling and Simulation Framework (MMSF), a theory of (multiscale) model coupling that explains how different coupling patterns can be used to connect submodels simulating processes across domains and spatiotemporal scales. It shows examples of different kinds of couplings from applications in different fields, and present MUSCLE3, a model coupling tool that implements the MMSF in an easy-to-use software package that can run simulations locally and on High-Performance Computing machines. Lourens Veen is a Senior Research Software Engineer at the Netherlands eScience Center. Originally a computer scientist, he now mostly works in various branches of computational science. He is interested in coupled simulations, validation, verification and uncertainty quantification (VVUQ), and accessible high-performance computing. For more information see: https://muscle3.readthedocs.io/en/latest/ *Contents* 00:00 - Introduction 06:58 - Coupled Simulations in Theory and Practice 35:39 - Questions and Discussion Moderator: James A. Glazier, PhD, Indiana University, Bloomington If you found this video useful, please check out our other videos on computational modeling, infection and immunology: https://youtube.com/playlist?list=PLiEtieOeWbMKh9VcQoinSwODcSZKMTGat Please consider joining our IMAG/MSM WG on Multiscale Modeling and Viral Pandemics: https://www.imagwiki.nibib.nih.gov/content/msm-viral-pandemics-meetings Please also consider joining the Global Alliance for Immune Prediction and Intervention: http://glimprint.org/