James Sluka
jsluka@indiana.edu
Biocomplexity Insitute
Indiana University, Bloomington, Indiana
Indiana University, Bloomington, Indiana
Lab Site
Publications
Research Description
My primary interests are in multiscale modeling of biological systems. My current work at the Biocomplexity Institute includes the development of (1) modeling-language standards (e.g., the Cell Behavior Ontology) and Iinternatiaonl Standards (ISO) , (2) multiscale vascular, liver and epithelial simulations (3) coupling subcellular reaction kinetics and whole body ADME models to multicell models, and (4) drug modeling such as toxicity and bioavailability issues. Currently, I am part of the team developing and maintaining CompuCell3D, a multiscale modeling package. I also have extensive experience in cheminformatics, bioinformatics and software development with emphasis on modeling and text mining tools. I was the lead developer of the Cell Behavior Ontology, which links biological concepts to their instantiation in computer models. I am currently involved in standards development projects and I am a voting member of the International Organization for Standards (ISO) committee on data standards in biotechnology. In 2020 I contributed to a rapid pivot to model development for COVID-19. I am a founding member of an IMAG/MSM working group on modeling for viral pandemics (https://www.imagwiki.nibib.nih.gov/working-groups/multiscale-modeling-and-viral-pandemics).
Subgroup Memberships