Publications

Medical ‘Digital Twins’ Will Lead the Way to Personalized Medicine

authors:
Richard Laubenbacher

Medical ‘Digital Twins’ Will Lead the Way to Personalized Medicine

Design specification for Critical Illness Digital Twins to cure sepsis

authors:

A design specification for Critical Illness Digital Twins to cure sepsis: responding to the National Academies of Sciences, Engineering and Medicine Report: Foundational Rese

Comparative Computational Modeling of the Bat and Human Immune Response to Viral Infection

developers:

WHAT IS IT?: This agent based model examines differences in innate immune mechanisms between bats and humans.

Sego et al: Multiscale acute primary infection and response in epithelium

developers:
Sego TJ, Aponte-Serrano JO, Ferrari Gianlupi J, Heaps SR, Breithaupt K, Brusch L, Crawshaw J, Osborne JM, Quardokus EM, Plemper RK, Glazier JA.

This model describes select interactions between generalized epithelial and immune cells and their extracellular environment associated with viral infection and immune response at the cellular and

The role of syncytia during viral infections.

authors:
Jessie B, Dobrovolny HM

Rapid community-driven development of a SARS-CoV-2 tissue simulator.

authors:
Getz M, Wang Y, An G, Becker A, Cockrell C, Collier N, Craig M, Davis CL, Faeder J, Ford Versypt AN, Ferrari Gianlupi J, Glazier JA, Hamis S, Heiland R, Hillen T, Hou D, Aminul Islam M, Jenner A, Kurtoglu F, Liu B, Macfarlane F, Maygrundter P, Morel PA, N

A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its application to drug therapy timing and effectiveness.

authors:
Sego TJ, Aponte-Serrano JO, Ferrari Gianlupi J, Heaps SR, Breithaupt K, Brusch L, Osborne JM, Quardokus EM, Plemper RK, Glazier JA.

A Modular Computational Framework for Medical Digital Twins.

authors:
Masison, J., J. Beezley, Y. Mei, H. a. L. Ribeiro, A. C. Knapp, L. Sordo Vieira, B. Adhikari, Y. Scindia, M. Grauer, B. Helba,W. Schroeder, B. Mehrad, R. Laubenbacher.

Using digital twins in viral infection.

authors:
Laubenbacher R, Sluka JP, Glazier JA.

Lives and Costs Saved by Expanding and Expediting Coronavirus Disease 2019 Vaccination.

authors:
Sarah M Bartsch, Patrick T Wedlock, Kelly J O’Shea, Sarah N Cox, Ulrich Strych, Jennifer B Nuzzo, Marie C Ferguson, Maria Elena Bottazzi, Sheryl S Siegmund, Peter J Hotez, Bruce Y Lee